18, January 2020
Hepatitis D coinfection found in ‘household clusters’ in Cameroon 0
Investigation into the epidemiology of hepatitis D in Cameroon revealed intrahousehold infection and large differences in prevalence between regions, with cases concentrated in forested areas close to the equator, which has been seen in other tropical areas.
“Central Africa has the unfortunate peculiarity of being highly endemic for infection with HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis delta virus (HDV) so that concomitant infections with more than one of these pathogens occur frequently,” Arnaud Fontanet, MD, DrPH, from the Institut Pasteur in Paris, France, and colleagues wrote. “While much attention has been paid to the first three, relatively little is known about the epidemiology of HDV and its interactions with the other blood-borne viruses. Here, we extend [previous work in HCV] to HBV and HDV, and investigate the distribution and risk factors of HDV infection in Cameroon.”
Of the 14,510 participants in the study, 1,621 (11.9%) were positive for HBV surface antigen and 224 of those with HBV were seropositive for HDV. These data led to an estimate of 1,160,799 HBsAG-positive individuals and 122,910 HDV-seropositive individuals in the 15 years to 49 years age group in 2011.
While HDV antibody prevalence did not vary by sex or age, the researchers found variations between regions and ethnic groups. The HDV prevalence was 50% in Sud and 54% in Est, whereas the prevalence ranged between 1% and 19% in the remaining 10 regions (P < .0001). By similar variance, HDV prevalence was 49% among Eastern Bantus and 25% in Southern Bantus, whereas the prevalence ranged between 3% and 8% in the remaining ethnic groups. (P < .0001).
Additionally, the researchers observed a “pronounced South to North gradient” in HDV prevalence, from 28.3% under 4°N down to 4.2% above 9.6° N.
Among the 239 households with at least two individuals with HBV, if HDV seropositivity was randomly distributed across individuals of these households, the expected number of households with at least one case of HDV seropositivity would be 48 (95% CI, 44-50).
However, the observed number was 31, which Fontanet and colleagues noted was significantly lower than expected and suggested an intra-household clustering of cases. Similarly, the observed number of houses with two or more cases of HCV seropositivity was significantly higher than expected by chance, indicating clustering of infected individuals within a household.
“It is noteworthy that in the family with four chronically infected with HBV, all four were co-infected with HDV,” they wrote. “Likewise, of the three families with all three chronically infected with HBV, all three were coinfected with HDV in two families, and two out of three were co-infected with HDV in the remaining.”
Source: Healo.com
18, January 2020
Biya, even rulers for life don’t live forever 0
A head of state is only as good as the counsel he seeks and the counselors who provide it. This is true as many celebrated leaders around the globe surrounded themselves with men and women with solid personal achievements. French Cameroun dictator, Paul Biya rejected every top aide that state institutions provided for him when he took office in 1982 and systematically burned through so many top Francophone and Anglophone advisers and so much good will that he now operates with a hollowed-out tribal staff of half-baked academic and political experience.
This explains why, 4 gendarmerie officers killed by Nigerian smugglers in Agborkem German in the Manyu County was misinterpreted as a crime committed by Southern Cameroons separatists and a war was declared against the English speaking communities that has eventually laid to rest the doctrine of the United Republic of Cameroon or better still, the one and indivisible Cameroon.
Everyone deep within the consortium of the ruling CPDM crime syndicate is now exhausted by Biya’s moods, offended by his shabby treatment of them and astonishingly shocked by his ignorance and low sense of judgment. The silence currently being maintained by men like Joseph Owona, Sultan Ibrahim Mbombo Njoya, Peter Mafany Musonge and Philemon Yang is indeed a conclusion that if Biya is an institution, CPDM is no longer trustworthy.
The numerous lies regularly told by Biya and his gang of French Cameroun political elites show that his so-called “Special Status” for the people of Southern Cameroons cannot be accepted. In declaring war against the English speaking people of Southern Cameroons-Ambazonia, Biya embraced a French government course that his predecessor, the late Ahmadou Ahidjo rejected as too extreme in the days of Ndeh Ntumazah’s One Kamerun.
Following several incremental breaches of all accords signed in Foumban in 1961 with Southern Cameroons political leadership, Biya is now running away from the Etoudi palace in Yaoundé. Age is telling on him and his ancestors are calling!! The average length of his numerous stay in his Mvomeka’a palace has gradually lengthened: whereas he spent only a few days each time a few years ago, he now stays there for several weeks in a row, or even more than a month.
The people of Southern Cameroons have made it crystal clear that they are no longer an item with La Republique du Cameroun. The recent massive deployment of troops to Southern Cameroons and the upcoming February polls have escalated tensions to perilous heights between the Biya regime and Ambazonia Interim Government.
A spokesperson for the Ambazonia Vice President Dabney Yerima was quoted lately as saying the Southern Cameroons Interim Government was responding to French Cameroun’s massive military deployments with massive resistance. There are no signs of de-escalation, Buea and Yaoundé could be heading for a divorce absolute.
Third-party mediation is not on sight which many have opined is the best mechanism for finding a solution to the crisis.
To understand why President Biya who will be 87 this February is still holding on to power, start with a simple fact. Ever since the attempted coup on April 6th 1984, President Biya’s regime has killed too many Cameroonians both at home and abroad including his first wife Jeanne-Irène Biya that he was married for 32 years (until 1992) and embezzled and wasted too many billions of Cameroonian money, to make it plausible that he would ever voluntarily give up power.
Under the current La Republique du Cameroun constitution, President Biya can run again and again for president when his term expires in six years time. To be sure, the constitution and elections do not much matter in Cameroon. La Repubique du Cameroun is a crime syndicate and dictatorship masquerading as a democracy. You simply need French government support and some lobby firms deep within the European Union and in the USA with little or no economic growth and corruption to remain as head of state.
Biya and his gang control the state radio and television, he bars popular opposition candidates from participating in elections, his regime regularly co-opt tame French Cameroun opposition figures and arrests and intimidation are dished out to the less tame ones. He has support from Nigeria’s President Buhari who as a soldier makes little secret of his admiration for strongmen. With Southern Cameroons gone, French Cameroun only comfort is that even rulers-for-life such as the Monarchs don’t live forever.
By Soter Tarh Agbaw-Ebai