15, June 2018
Hong Kong scientists say new research points to universal antibody drug for HIV 0
A team of AIDS researchers in Hong Kong says its new research, tested on mice, indicates a functional cure for HIV, the virus that causes AIDS, eventually leading to a new antibody that could be used for both prevention and treatment.
The findings, published in the Journal of Clinical Investigation, come as China faces a growing epidemic among high-risk groups, such as sex workers and men who have sex with men.
The UN-supported AIDS Data Hub says about 850,000 people in China are infected with HIV, which disables the immune system and makes people far more vulnerable to infections and disease.
A team led by Professor Chen Zhiwei at Hong Kong University’s AIDS Institute says its discovery, tested on mice, shows the new antibody can help control the virus and eliminate infected cells.
The antibody would be able to treat all varieties of HIV – a first, Chen said – as there is no one vaccine to treat the many different types of HIV viruses.
“For our newly discovered bispecific antibody, it works for all of them, so that’s the major difference,” Chen told Reuters.
Chen and his team say they aim to bring the antibody into clinical trials within a timeframe of three to five years.
Chen said a “functional cure” meant the virus level would be so low as to be undetectable in the body, as long as patients kept taking injections of the antibody, perhaps on a quarterly basis, or less frequently.
Those infected with HIV can keep the virus under control with antiretroviral drugs that stop it from infecting new cells.
However, treatments must be taken daily and do not eliminate the infected cells from the body. So the virus can still exist, and symptoms return, if patients stop taking medication properly.
The new antibody would have a significantly longer half-life than current treatments, and could, for example, be administered on a quarterly basis, Chen said, making it easier than the daily treatment most HIV-infected patients face.
Promising results did not mean the treatment would be readily available soon, said Andrew Chidgey, chief executive of the charity group AIDS Concern in Hong Kong.
“Governments are being very slow to implement programmes here,” he added. “So just because a treatment becomes available, doesn’t mean that people will get it, or that it will have an impact.”
(Source: Reuters)
20, June 2018
Southern Cameroons Crisis Shut Down Schools 0
It is a bright Tuesday morning, with children hawking goods to drivers and passersby on the congested streets of Yaounde. The number of these sidewalk sellers is increasing with the ongoing conflict in Cameroon’s English-speaking northwest and southwest regions, where fighting between armed separatists and government troops has shut down schools and sent thousands of children fleeing to safer ground.
Among the sidewalk peddlers is 16-year-old Delphine Tabe. She says she has been a hawker for more than a year since she fled from her village in Lebialem, an administrative unit in the southwest.
“I am selling boiled groundnuts to have money and help my mother who is in the hospital. She was beaten by Cameroon gendarmes after a military man was killed in our village. My mother almost died. Our school was burned and students were beaten. Since that day in May 2017, we escaped to Yaounde and we do not have money to go to school.”
Delphine says her chances of pursuing her dream – becoming a teacher – are gradually slipping away as she has no one to sponsor her education. Instead, she has to look for money to help her sick mother.
In the kitchen at the house where Delphine lives in Yaounde, food is being prepared for 32 people. Emmanuel Nembo, a 52-year old government worker originally from Lebialem, says that a year ago, he had only five mouths to feed.
The number exploded as people from the southwest fled their villages and pleaded for him to feed and shelter them.
Emmanuel says he is praying for the crisis to stop because many have been coming and he can no longer offer help.
“We are stretching an olive hand of peace. Those in the bush should give a chance. Come back home, to their homes so that they could meet their mothers, brothers and sisters,” he says.
Many schools have been closed in the northwest and southwest areas since November 2016, when lawyers and teachers began a strike to stop what they see as the overbearing use of French.
Separatists took over the movement, and began pushing for the regions to become independent.
Since then, several dozen schools have been torched, and armed men have kidnapped or killed a number of teachers. Many students in the regions can no longer attend the few schools that are still open, for fear of the unknown.
The United Nations estimates that more than 100,000 people, a majority of them children of school age, have fled the violence in the English-speaking regions for safer locations. Tens of thousands have crossed over to Nigeria, and no one knows when any of them will ever return to school.
Source: VOA